Termination of atrial fibrillation by ablation of high-dominant frequency sites adjacent to epicardial adipose tissue

Epicardial Adipose Tissue Thickness and Ablation Outcome of Atrial Fibrillation

OBJECTIVES Epicardial fat was closely related to atrial fibrillation (AF). Transthoracic echocardiography (TTE) has been proposed to be a convenient imaging tool in assessing epicardial adipose tissue (EAT). The goal of the present study was to investigate whether the EAT thickness measured on TTE was a useful parameter in predicting procedural outcomes of AF ablations. METHODS AND RESULTS A ...

Does location of epicardial adipose tissue correspond to endocardial high dominant frequency or complex fractionated atrial electrogram sites during atrial fibrillation?

BACKGROUND Although increased epicardial adipose tissue (EAT) volume is known to be associated with increased prevalence of atrial fibrillation (AF), the exact mechanisms are unclear. Therefore, we investigated whether EAT locations were associated with high dominant frequency (DF) sites or complicated fractionated atrial electrogram sites during AF. METHODS AND RESULTS Three-dimensional reco...

Epicardial adipose tissue and atrial fibrillation.

Atrial fibrillation (AF) is the most frequent cardiac arrhythmia in clinical practice. AF is often associated with profound functional and structural alterations of the atrial myocardium that compose its substrate. Recently, a relationship between the thickness of epicardial adipose tissue (EAT) and the incidence and severity of AF has been reported. Adipose tissue is a biologically active orga...

Atrial Fibrillation Ablation by the Epicardial Approach.

Catheter ablation is an effective treatment for atrial fibrillation (AF). However, over long-term follow-up, it is becoming clear that AF often recurs and repeat ablation is required. With the goal of improving efficacy, particularly in those patients with risk factors for poor outcomes using a standard endocardial ablation technique, surgical epicardial ablation has emerged as an alternative m...

Epicardial adipose tissue and neural mechanisms of atrial fibrillation.